Research

Professor of Ophthalmology for Glaucoma and Allied Studies

Donations, legacies, and membership fees helps to fund the position of IGA Chair of Ophthalmology for Glaucoma and Allied Studies. This is a dedicated role, governed through a separate charitable trust (charity number: 1123188) with the specific purpose to advance education about glaucoma, and ensure that research is published. The current holder of the post is Professor David Garway-Heath who is the IGA Professor at the University of London's Institute of Ophthalmology.

2017 Research grants 

The IGA works with a range of professional bodies to provide funding for glaucoma research. During 2016 and 2017, the IGA is awarding £220,000 to help with the detection, diagnosis and treatment of glaucoma. Full details can be found on the links below:

UK and Eire Glaucoma Society, 30th September 2016

Royal College of Ophthalmologists, 3rd February 2017 

Royal College of Nursing, 31st March 2017 

The College of Optometrists 5th May 2017

 

 Research grants

"The IGA funding schemes have been instrumental in establishing and developing glaucoma research within Liverpool both in the clinic and laboratory. IGA funding provides a variety of grants including pump-priming funding to develop innovative ideas, and also to support junior ophthalmologists to participate in glaucoma research and become future leaders.  Personally and within my research group we are extremely indebted to the support of the IGA. This funding has helped establish new datasets, experimental models and infrastructure which has already helped us secure larger funding from Research Councils. The glaucoma community in the UK is privileged to have the support of the IGA and I would like to thank you all for your continued support in tackling this significant eye disease." Professor Colin Willoughby, University of Liverpoool.  

Here are some examples of the research we have funded:

Mitochondrial Dysfunction in the Commonest Form of Glaucoma: University of Liverpool

A Liverpool based research project to improve treatments and quality of life for glaucoma patients.   The IGA together with the UK and Eire Glaucoma Society (UKEGS) is funding research by Dr Neeru Vallabh of the University of Liverpool to understand the role mitochondrial defects and mutations play in the development of the commonest form of glaucoma: primary open angle glaucoma (POAG).

Dr Vallabh explains: Our lack of understanding of the causes of glaucoma is a major obstacle to the development of new therapeutic approaches for this significant condition. Identifying the role of mitochondrial defects and mutations in the development of glaucoma will increase our understanding of this common, sight-threatening condition.’

Patients’ and Carers’ Perspectives of Managing Glaucoma when Living with Dementia: University of Manchester

A joint research study with the Royal College of Nursing is being run by Professor Heather Waterman of the University of Manchester to better understand how people living with dementia manage a sight-threatening condition such as glaucoma.  About one in four people who have severe visual impairment from glaucoma also have a diagnosis of dementia. It is more difficult to assess and treat glaucoma when people also live with dementia and together they compound feelings of distress and disorientation.

This study aims to support the development of clinical guidance on how glaucoma services can be improved to meet the needs of people living with dementia.

Evaluation of Virtual clinics for Glaucoma Care: Central Manchester University

A  two-year joint study with UKEGS is being conducted by Robert Harper, Optometrist Consultant of Central Manchester University Hospitals NHS Foundation Trust, to evaluate patients’ and clinicians’ experiences of virtual monitoring clinics in the UK.

The past decade has seen different measures to monitor glaucoma patients with a number of NHS Trusts using ‘Virtual Clinics’ as part of the solution, where data is collected on the day a patient visits either a hospital or a community clinic, often using electronic patient records which are then analysed by an expert clinician without the patient being there.  Very little is known about patients’ experiences and perceptions of virtual clinics, or about clinicians’ opinions of them and the Central Manchester University Hospitals NHS Foundation Trust study will investigate this through online surveys, focus groups and interviews.

Robert Harper of Central Manchester University Hospitals NHS Foundation Trust says: ‘It is so fundamental to collate both the patient and practitioner viewpoints to inform the way in which we run our clinics and this virtual clinic research aims to address key deficiencies in information in this respect.’

Quality of life assessment in glaucoma patients undergoing glaucoma surgery: Nottingham University Hospital 

The IGA, together with, UKEGS is funding research by Professor Anthony King of Nottingham University Hospital to profile the quality of life of glaucoma patients at different stages of treatment. The study will look at whether patients’ personalities affect the outcome of their glaucoma treatment and will allow comparisons between alternative glaucoma approaches.  This will enable clinicians to include accurate information in discussions about surgical options available and in patient information about proposed treatments.

Professor King explains: ‘Quality of Life is a measure of the patient’s health and this is affected by the medical conditions from which they suffer and the treatments they experience.  In glaucoma many patients require glaucoma surgery, and, in addition to undergoing an operation, this also results in frequent hospital visits and often a very intensive eye drop regime. Understanding the way glaucoma interventions impact on a patient’s quality of life and the different impacts of the various available interventions would be helpful in counselling patients prior to surgery and informing their expectations.’

Finding glaucoma in the high street – a pop up pilot project: College of Optometrists 

Risk of visual impairment from glaucoma is greatest in those patients detected at a late stage of the disease. Also patients living in the most deprived areas of the UK, as estimated by postcode data, are predicted to be diagnosed with twice as much vision loss compared to those from the least deprived regions. The IGA together with the College of Optometrists is funding an 18 month research project in association with Deanna Taylor and Professor David Crabb of City University London, to hold pop up glaucoma testing clinics to see if public engagement or detection rate of suspect glaucoma is greater in ‘deprived’ areas, compared to more ‘prosperous’ areas.

Professor Crabb of City University London comments Retail pop up booths in high streets and in shopping centres are common – we propose one for glaucoma! The idea is to move glaucoma detection to communities that we think are hard to reach. The IGA funding allows us to pilot the feasibility of glaucoma testing on the high street – literally!’

Please contact J.McCarthy@iga.org.uk if you would like more information on how to fund these research programmes.

 research

 Annual lectures

To find out more about our research funding click on the links below for transcripts of the annual lectures provided by our guest speakers

Mitochondria and Glaucoma- Professor Colin Willoughby (IGA news- Summer 2016)

'In, out and about', Glaucoma Eye Drop Delivery- Professor Clive Wilson (IGA news- Spring 2016)

2015 Research update- Professor David Garway-Heath (IGA news- Winter 2015)

The UK Biobank Project and the Glaucoma Data Analysis Research Project (Closed Angle Glaucoma)- Professor Paul Foster (IGA news- Autumn 2015)

Driving and Glaucoma- Consultant Ophthalmologist Ananth Viswanathan (IGA news- Summer 2015)

What's new in the treatment of Glaucoma- Consultant Eye Surgeon Andrew Tatham (IGA news- Spring 2015)

Research Update- Karen Brewer- Head of Marketing & PR (IGA news- Winter 2014)

2014 Research update- Professor David Garway-Heath (IGA news- Autumn 2014)

Glaucoma through the eyes of the patient- Professor David Crabb (IGA news- Summer 2014)

Studying Blindness, there's an app for that- Dr Andrew Bastawrous (IGA news- Spring 2014)

Explaining Glaucoma- Dr Donald Montgomery (IGA news- Winter 2013)

Recent issues with glaucoma medication- Lead Ophthalmic Pharmacist Lucy Titcomb (IGA news- Autumn 2013)

Stem cells and other new approaches to glaucoma- Professor of Ophthalomolgy Keith Martin (IGA news- Summer 2013)

How glaucoma impacts vision- Consultant Ophthalmologist Dr Caroline Cobb- Summer open patient meeting (IGA news- Spring 2013)

How does glaucoma look? Patient perception of visual field loss- Professor David P Crabb (IGA news- Winter 2012)

Research updates (IGA news- Autumn 2012)

Patient involvement in standards of care, outcomes and research- Consultant ophthalmologisy- Mr Richard Wormald (IGA news- Summer 2012)

The glaucoma journey- Consultant Ophthalmoc Surgeon- Anne Fiona Spencer (IGA news- Spring 2012)

The development and testing of an education programme delivered to a group of patients to improve adherence with glaucoma eye drops- Professor Heather Waterman and Jill Annis (IGA news- Winter 2011)

The importance of IGA glaucoma database 2011- Dr Anne Child (IGA news- Autumn 2011)

The use of cyclodiode laser treatment in glaucoma- 17 years of the Nottingham protocol- Professor Stephen A Vernon (IGA news- Summer 2011)

The Moorfields Motion Displacement Test (MDT) (IGA news- Spring 2011)

An investigation into the genetic basis of Primary angle-closure glaucoma- Dr Sancy Low (IGA news- Winter 2010)

The role of Thrombospondin 1 and 2 in open angle glaucoma - Mr Anshoo Choudary- Consultant Ophthalmologist and Clinical Lecturer (IGA news- Autumn 2010)

Glaucoma, NICE and the Community Optometrist-Geoff Roberson, Professional Advisor (Association of Optometrists) (IGA news- Summer 2010)

Glaucoma research and the IGA: Addressing the major issues- Professor David Garway- Heath (Spring 2010)